Collagen

Collagen hydrolysate

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Hays NP, Kim H, Wells AM, Kajkenova O, Evans WJ. Effects of whey and fortified collagen hydrolysate protein supplements on nitrogen balance and body composition in older women. Journal of the American Dietetic Association 2009;109(6):1082-7.

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Iwai K, Hasegawa T, Taguchi Y, Morimatsu F, Sato K, Nakamura Y, Higashi A, Kido Y, Nakabo Y, Ohtsuki K. Identification of Food-Derived Collagen Peptides in Human Blood after Oral Ingestion of Gelatin Hydrolysates. Journal of Agricultural and Food Chemistry 2005;53:6531-6536.

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Lee SK, Posthauer ME, Dorner B, Redovian V, Maloney MJ. Pressure ulcer healing with a concentrated, fortified, collagen protein hydrolysate supplement: a randomized controlled trial. Advances in Skin and Wound Care 2006;19(2):92-6.

Li F, Jia Dongying, Yao K. Amino acid composition and functional properties of collagen polypeptide from Yak (Bos grunniens) bone. Food Science and Technology 2009;42:945-949.

Martin-Bautista E. Marint-Matillas M, Maring-Lagos JA, Miranda-Leon MT, Muñoz-Torres M, ruiz-Requena E, Rivero M, Quer J, Puigdueta I, Campoy C. A nutritional intervention study with hydrolyzed collagen in pre-pubertal Spanish children: influence on bone modeling biomarkers. Journal of Pediatric Endocrinology and Metabolism 2011;24(3-4):147-53Oesser S, Adam M, Babel W, Seifert J. Oral administration of 14C labeled gelatin hydrolysate leads to an accumulation of radioactivity in cartilage of mice (C57/BL). Journal of Nutrition 1999;129(10):1891-5.

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Oesser S, Adam M, Babel W, Seifert J. Oral administration of 14C labeled gelatin hydrolysate leads to an accumulation of radioactivity in cartilage of mice (C57/BL). Journal of Nutrition 129(10):1891-5, 1999.

Oesser S, Seifert J. Stimulation of type II collagen biosynthesis and secretion in bovine chondrocytes cultured with degraded collagen. Cell and Tissue Research`2003;311(3):393-9.

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Schauss AG, Merkel DJ, Glaza SM, Sorenson SR. Acute and subchronic oral toxicity studies in rats of a hydrolyzed chicken sternal cartilage preparation. Food and Chemical Toxicology 2007;45(2):315-21.

Schauss AG, Stenehjem J, Park J, Endres JR, Clewell A. Effect of the novel low molecular weight hydrolyzed chicken sternal cartilage extract, BioCell Collagen, on improving osteoarthritis-related symptoms: a randomized, double-blind, placebo-controlled trial. J Agric Food Chem. 2012 Apr 25;60(16):4096-101

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Sieper J, Kary S, Sörensen H, Alten R, Eggens U, Hüge W, Hiepe F, Kühne A, Listing J, Ulbrich N, Braun J, Zink A, Mitchison NA. Oral type II collagen treatment in early rheumatoid arthritis. A double-blind, placebo-controlled, randomized trial. Arthritis and Rheumatism 1996;39(1):41-51.

Sundell MB, Cavanaugh KL, Pingsheng W, Shintani A, Hakim RM, Ikizler TA. Oral Protein Supplementation Alone Improves Anabolism in a Dose-Dependent Manner in Chronic Hemodialysis Patients. Journal of Renal Nutrition 2009;19(5):412-421.

Trentham DE, Dynesius-Trentham RA, Orav EJ, Combitchi D, Lorenzo C, Sewell KL, Hafler DA, Weiner HL.Effects of oral administration of type II collagen on rheumatoid arthritis. Science 1993;261(5129):1727-1730.

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USP 35: United States Pharmacopeia and the National Formulary (USP 35 – NF 30). Rockville (MD): The United States Pharmacopeial Convention; 2012.

Veis A. The macromolecular chemistry of gelatine. New York (NY): Academic Press, 1964.

Ward AG and Courts A. The Science and Technology of Gelatin. London (GB): Academic Press, 1977.

Wei W, Zhang LL, Xu JH, Xiao F, Bao CD, Ni LQ, Li XF, Wu YQ, Sun LY, Zhang RH, Sun BL, Xu SQ, Liu S, Zhang W, Shen J, Liu HX, Wang RC. A multicenter, double-blind, randomized, controlled phase III clinical trial of chicken type II collagen in rheumatoid arthritis. Arthritis Res Ther. 2009;11(6):R180.

Wu J, Fujioka M, Sugimoto K, Mu G, Ishimi Y. Assessment of effectiveness of oral administration of collagen peptide on bone metabolism in growing and mature rats. Journal of Bone and Mineral Metabolism 2004;22(6):547-53.

Zhang Z, Li G, Shi B. Physiochemical properties of collagen, gelatin and collagen hydrosylate derived from bovine lime split wastes. Journal of the Society of Leather Technologists and Chemists 2006;90(1):32-28.

Zhao W, Tong T, Wang L, Li PP, Chang Y, Zhang LL, Wei W. Chicken type II collagen induced immune tolerance of mesenteric lymph node lymphocytes by enhancing beta2-adrenergic receptor desensitization in rats with collagen-induced arthritis. International Immunopharmacology 2011;11(1):12-8.

Zuckley L, Angelopoulou KM, Carpenter MR, McCarthy S, Meredith BA, Kline G, Rowinski M, Smith D, Angelopoulos TJ, Rippe JM. Collagen Hydrolysate Improves Joint Function in Adults with Mild Symptoms of Osteoarthritis of the Knee. Medicine and Science in Sports and Exercise 2004;36(5):S153-S154.

See references for amylase